Description: Cholvax for oral use, is a turbid, white or brownish suspension free of aggregates and extraneous particles. The vaccine is formulated with required quantity of V. cholerae O139 and O1 (serotypeInaba and Ogawa) inactivated by heat and formaldehyde. Indications: Cholvax is indicated for active immunization against Vibrio cholerae. The vaccine can be administered to anyone above the age of 1 year. Data for the safety and efficacy of the vaccine in infants (less than 1 year of age) is not available. The earliest onset of protection can be expected 7-10 days after the completion of the primary series of the vaccine. Efficacy against Vibrio cholerae serogroup O139 was not demonstrated. Dosage and Administration: The recommended dose of the vaccine (1.5 ml) is to be administered orally. The primary immunization schedule consists of two doses given at an interval of at least two weeks. Cholera vaccine should not be administered parenterally (intramuscular, subcutaneous or intravenously). The vaccine is only recommended for oral administration. Method of administration The vaccine is presented as a suspension. After vigorous shaking of the vial, 1.5 ml should be poured into the mouth of the recipient. The vaccine administration may be optionally followed by water to facilitate ingestion, if needed. The vaccine can alternatively be administered with a disposable syringe (without needle) after removing the contents from the vial and squirted into the mouth of the recipient. The vaccine should not be administered parenterally (intramuscular, subcutaneous or intravenously). The vaccine is only recommended for oral administration.
Presentation: Cholvax : Each vial contains 1.5 ml Inactivated Oral Cholera Vaccine BP as- Active ingredients: V. cholerae O1 Inaba Phil 6973 El Tor, Formaldehyde Inactivated 600 LEU* V. cholerae O1 Inaba Cairo 48, Heat Inactivated 300 LEU V. cholerae O1 Ogawa Cairo 50, Formaldehyde Inactivated 300 LEU V. cholerae O1 Ogawa Cairo 50,Heat Inactivated 300 LEU V. cholerae O139 4260B, Formaldehyde Inactivated 600 LEU Excipients: Thiomersal 0.15 mg PBS (Phosphate buffer saline) q.s to 1.5 ml